DOSINA

Tianeptine

Medication

An atypical antidepressant that acts on opioid receptors at higher doses. Included for interaction checking — it adds to opioid and respiratory-depression risk.

StablonCoaxilTatinol

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Prescription or supplement entry — included for interaction checking, not as recreational dose guidance. Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

Dose

Published population range

Threshold3 mg
Light6–12 mg
Common12–35 mg
Strong35–100 mg
Heavy / risk zone≥ 100 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (oral)

Onset30–60 minutes
Come-up15–30 minutes
Peak60–90 minutes
Offset30–60 minutes
Total120–180 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • Mood lift (prescription in some countries)

Possible side effects

  • Opioid-like effects at higher doses
  • Dependence
  • Severe withdrawal
  • Respiratory depression when mixed with depressants

Known toxicity

  • large therapeutic index and margin of safety

Harm reduction

  • Dosina shows prescription medicines so their interactions are visible - not so you can use them recreationally.
  • Never stop a prescribed medicine abruptly to take something else. Antidepressant discontinuation syndrome is real and can be severe; talk to your prescriber first.
  • SSRIs, SNRIs, MAOIs, lithium and tricyclics all interact with recreational drugs in ways that range from 'wastes your money' to 'kills you'.
  • Serotonin syndrome is the emergency to watch for: agitation, confusion, tremor, sweating, muscle rigidity, fever and a fast heartbeat after combining serotonergic drugs. It can become fatal within hours.
  • Keep any prescription medicine in its original packaging and never share it.

Identify what you have

Marquisno color change (254)
Liebermannno color change (73)
Froehdeno color change (241)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Tolerance, dependence and detection

Tolerancehalf tolerance after 3 - 7 days; back to baseline after 1 - 2 weeks
Addiction potentialmildly addictive
After-effects1-8

Sources

• PsychonautWiki — Tianeptine (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/Tianeptine

• TripSit wiki — Tianeptine (PolyForm Noncommercial)
https://wiki.tripsit.me

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.