DOSINA

Sertraline

Medication

A commonly prescribed SSRI antidepressant. Included for interaction checking rather than as dose guidance: it does not make MDMA safe, it only makes it weaker and more dangerous to mix.

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Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Not covered by PsychonautWiki — data comes from TripSit. Prescription or supplement entry — included for interaction checking, not as recreational dose guidance. Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

Dose

No structured dose data for this substance in our sources. Treat anything you read elsewhere with caution - unknown potency is the single biggest risk with novel substances.

Expected effects

  • Mood stabilisation over weeks (prescription antidepressant)

Possible side effects

  • Nausea
  • Sexual dysfunction
  • Serotonin syndrome with serotonergic drugs
  • Discontinuation syndrome
  • Blunts MDMA effects without making the combination safe

Harm reduction

  • Dosina shows prescription medicines so their interactions are visible - not so you can use them recreationally.
  • Never stop a prescribed medicine abruptly to take something else. Antidepressant discontinuation syndrome is real and can be severe; talk to your prescriber first.
  • SSRIs, SNRIs, MAOIs, lithium and tricyclics all interact with recreational drugs in ways that range from 'wastes your money' to 'kills you'.
  • Serotonin syndrome is the emergency to watch for: agitation, confusion, tremor, sweating, muscle rigidity, fever and a fast heartbeat after combining serotonergic drugs. It can become fatal within hours.
  • Keep any prescription medicine in its original packaging and never share it.

Sources

• TripSit wiki — Sertraline (PolyForm Noncommercial)
https://wiki.tripsit.me

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.