DOSINA

Propranolol

Medication

A beta-blocker (prescription medicine). Included because it can mask the warning signs of stimulant overdose, and combining it with cocaine causes unopposed vasoconstriction.

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Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Not covered by PsychonautWiki — data comes from TripSit. Prescription or supplement entry — included for interaction checking, not as recreational dose guidance. Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

Dose

Published population range

Light10–30 mg
Common40–80 mg
⚠Strong: 80-140mg..

No weight-based model for this substance — published ranges only.

Check an amount you already have

Expected effects

  • Slowed heart rate, reduced physical anxiety symptoms (prescription medicine)

Possible side effects

  • Low blood pressure and fainting
  • Fatigue
  • Can mask the warning signs of stimulant overdose
  • Dangerous with cocaine (unopposed vasoconstriction)

Harm reduction

  • Dosina shows prescription medicines so their interactions are visible - not so you can use them recreationally.
  • Never stop a prescribed medicine abruptly to take something else. Antidepressant discontinuation syndrome is real and can be severe; talk to your prescriber first.
  • SSRIs, SNRIs, MAOIs, lithium and tricyclics all interact with recreational drugs in ways that range from 'wastes your money' to 'kills you'.
  • Serotonin syndrome is the emergency to watch for: agitation, confusion, tremor, sweating, muscle rigidity, fever and a fast heartbeat after combining serotonergic drugs. It can become fatal within hours.
  • Keep any prescription medicine in its original packaging and never share it.

Tolerance, dependence and detection

After-effects1-8

Sources

• TripSit wiki — Propranolol (PolyForm Noncommercial)
https://wiki.tripsit.me

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.