DOSINA

Pregabalin

Depressant

A prescription gabapentinoid: anxiolysis, relaxation and some euphoria. Steep dose-response, dizziness and sedation at higher doses, and real dependence with daily use.

LyricaNervalinlyricapregablin

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0).

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

Dose

Published population range

Threshold50 mg
Light50–225 mg
Common225–600 mg
Strong600–900 mg
Heavy / risk zone≥ 900 mg

Dose-response is steep and dizziness at higher doses is common.

Check an amount you already have

Timeline (oral)

Onset30–45 minutes
Come-up60–120 minutes
Peak240–360 minutes
Offset240–480 minutes
Afterglow240–600 minutes
Total540–1020 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • Anxiolysis
  • Relaxation
  • Mild euphoria
  • Sociability
  • Analgesia

Possible side effects

  • Dizziness and sedation
  • Blurred vision
  • Peripheral swelling
  • Dependence
  • Respiratory depression when mixed with opioids or benzodiazepines
  • Withdrawal

Known toxicity

  • low toxicity

Harm reduction

  • Depressants are the class where mixing kills most often: alcohol, benzodiazepines, GHB/GBL and opioids all suppress breathing when combined.
  • Never use alone. If you use alone, set up a check-in call with someone who will call emergency services if you do not answer.
  • Measure liquid doses with a syringe. Bottle caps, teaspoons and 'glugs' are how people take ten times the intended dose.
  • Sedation can be delayed. Do not re-dose before you can feel the previous dose fully.
  • Do not stop daily benzodiazepine or alcohol use abruptly - withdrawal can cause seizures and is potentially fatal. Taper with medical help.
  • Signs that someone needs emergency help: breathing slower than one breath every 4-5 seconds, blue lips, snoring that will not stop, unrousable, vomiting while unconscious.

Identify what you have

Marquisno color change (254)
Meckeno color change (221)
Mandelinno color change (139)
Liebermannno color change (73)
Froehdeno color change (241)
Ehrlichno color change (168)
Robadope (reacts)pink (11)
Simon's (reacts)purple (15)
Hofmannno color change (137)
Zimmermann (reacts)no change / faint yellow (20)
Morris (reacts)pale green (77)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

OxycodoneCaution

See interaction notes for details.

SSRICaution

See interaction notes for details.

MDMACaution

See interaction notes for details.

Tolerance, dependence and detection

Toleranceback to baseline after 7 - 14 days
After-effects1-12

Sources

• PsychonautWiki — Pregabalin (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/Pregabalin

• TripSit wiki — Pregabalin (PolyForm Noncommercial)
https://wiki.tripsit.me

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.