Oxycodone

Opioid · popular

A prescription opioid with strong analgesia and euphoria. Widely counterfeited; pills bought on the illicit market are one of the most common fentanyl vectors.

OxyContinOxyRoxicodoneOxectaOxyIREndoneOxynorCodilekOxydorRedocamOxygesicPercodan

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0).

Before you dose

⚠Dose here depends overwhelmingly on your tolerance, not your body weight. A dose that is mild for a tolerant user can be fatal for someone else.

⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold1 mg

Light2.5–7.5 mg

Common7.5–15 mg

Strong15–25 mg

Heavy / risk zone≥ 25 mg

Basis: Tolerance dominates; clinical dosing exists but is not applicable to non-prescribed use.

Never combine with benzodiazepines, alcohol or GHB — that combination drives most opioid deaths.

Check an amount you already have

Timeline (insufflated)

Onset2–7 minutes

Come-up20–40 minutes

Peak90–240 minutes

Offset45–120 minutes

Total180–300 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

Euphoria
Warmth
Strong analgesia
Relaxation
Anxiety relief

Possible side effects

Respiratory depression
Nausea and vomiting
Severe itching
Constipation
Tolerance and dependence
Widely counterfeited - fentanyl in pills

Known toxicity

low toxicity
potentially lethal when mixed with depressants like alcohol or benzodiazepines

Harm reduction

Never use alone. The single most effective thing you can do is have someone with you or on the phone.
Carry naloxone and know how to use it. It reverses opioid overdose and cannot harm someone who has not taken opioids.
Use fentanyl and nitazene test strips on every batch, including pills. They catch a large share of contamination, though not all of it.
Start with a fraction of your usual amount when you get a new batch or after any break in use - tolerance drops fast, in days.
Do not mix with benzodiazepines, alcohol, GHB or other sedatives. That combination is behind the majority of opioid deaths.
If someone is unresponsive: call emergency services, give naloxone, put them in the recovery position and stay with them. Naloxone wears off before many opioids do, so a second dose may be needed.
Prescribed opioid medication should never be shared or stockpiled - tolerance differences make it lethal.

Identify what you have

Marquis (TripSit reference)Pale violet

Marquis (reacts)slow faint purple (68)

Mecke (reacts)faint yellow > green (63)

Mandelin (reacts)orange / brown (234)

Liebermann (reacts)brown spots (113)

Froehde (reacts)yellow (78)

Ehrlichno color change (168)

Robadopeno pink color change (121)

Simon's (reacts)Dark pink (7)

Hofmannno color change (137)

Zimmermann (reacts)violet / purple (22)

Morris (reacts)pale green (77)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.