Psilocybin mushrooms

Psychedelic · popular

Psilocybin-containing mushrooms. A warm, flowy, often emotional psychedelic experience of 4-6 hours, usually with nausea on the come-up. Potency varies enormously between batches and species, so dried weight is an unreliable guide.

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Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0).

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold2.5 mg

Light2.5–10 mg

Common10–25 mg

Strong25–50 mg

Heavy / risk zone≥ 50 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (oral)

Onset20–45 minutes

Come-up60–90 minutes

Peak120–150 minutes

Offset150–210 minutes

Afterglow240–1440 minutes

Total360–480 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

Visual drifting, breathing surfaces and patterns
Emotional openness
Euphoria and mood lift
Introspection and insight
Connectedness with nature
Enhanced colours
Time distortion
Yawning and relaxed body feeling

Possible side effects

Nausea and stomach discomfort on the come-up
Anxiety and confusion
Muscle heaviness and weakness
Headache
Dilated pupils
Vomiting
Persisting perceptual changes with heavy use
Panic reactions in people vulnerable to psychosis

Known toxicity

extremely low toxicity relative to dose

Harm reduction

Dried weight tells you less than you would think - potency varies a lot between batches and species. Start at 1-1.5 g dried.
Assume around a 10:1 wet-to-dry ratio if you are using fresh mushrooms.
Nausea on the come-up is normal. Ginger, a light stomach and lying down help; fighting it does not.
Tolerance sets in within hours, so re-dosing later mostly extends the trip without adding depth. Leave 7-14 days between trips.
Avoid entirely if you or a close relative has a history of schizophrenia, psychosis or bipolar disorder.
Do not combine with lithium or tramadol.
Set and setting shape a psychedelic experience more than the dose does. Plan the room, the music, the company and the exit before you take anything.
Have a sober person present, or at minimum someone who knows what you have taken and can be called.
Do not redose to 'make it stronger'. Tolerance to psychedelics develops within an hour, so a redose mostly extends the experience and increases the risk of a difficult one.
Avoid combinations with lithium (seizure risk) and tramadol, and be extremely careful with cannabis, which sharply intensifies the experience.

Identify what you have

Marquis (reacts)orange (89)

Mecke (reacts)yellow green > brownish (156)

Ehrlich (reacts)purple (22)

Hofmann (reacts)yellow / green (18)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

LithiumDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

TramadolUnsafe

Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.

CannabisCaution

Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

AmphetaminesCaution

Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences

CocaineCaution

Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences

2c-t-xLow risk