Morphine

Opioid

The classic opioid: analgesia, warmth and sedation, with substantial respiratory depression at higher doses.

MS-ContinOramorphZomorphSevredolDuramorph

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0).

Before you dose

⚠Dose here depends overwhelmingly on your tolerance, not your body weight. A dose that is mild for a tolerant user can be fatal for someone else.

⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold3.33 mg

Light3.33–5 mg

Common5–7.5 mg

Strong7.5–10 mg

Heavy / risk zone≥ 10 mg

Basis: Tolerance dominates.

Oral morphine and morphine pills vary hugely in effective dose between people with different tolerance.

Check an amount you already have

Timeline (intravenous)

Onset0–0.5 minutes

Come-up2–5 minutes

Peak90–150 minutes

Offset60–90 minutes

Total240–300 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

Euphoria
Analgesia
Warmth
Sedation

Possible side effects

Respiratory depression
Nausea and vomiting
Itching
Constipation
Tolerance and dependence
Histamine release and flushing

Harm reduction

Never use alone. The single most effective thing you can do is have someone with you or on the phone.
Carry naloxone and know how to use it. It reverses opioid overdose and cannot harm someone who has not taken opioids.
Use fentanyl and nitazene test strips on every batch, including pills. They catch a large share of contamination, though not all of it.
Start with a fraction of your usual amount when you get a new batch or after any break in use - tolerance drops fast, in days.
Do not mix with benzodiazepines, alcohol, GHB or other sedatives. That combination is behind the majority of opioid deaths.
If someone is unresponsive: call emergency services, give naloxone, put them in the recovery position and stay with them. Naloxone wears off before many opioids do, so a second dose may be needed.
Prescribed opioid medication should never be shared or stockpiled - tolerance differences make it lethal.

Identify what you have

Marquis (reacts)red > (light) purple (68)

Mecke (reacts)sea greenish blue (13)

Mandelin (reacts)clear or grey (87)

Liebermann (reacts)blue / black (121)

Froehde (reacts)(dark) purple (42)

Robadopeno pink color change (121)

Simon'sno blue color change (163)

Scottno color change (65)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.