DOSINA

Modafinil

Stimulant

A wakefulness-promoting agent used for narcolepsy. Mild stimulation and focus without the euphoria of amphetamine, but it is not free of anxiety and cardiovascular effects.

AlertecModavigilModiodalProvigilModalertprovigil

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0).

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.
⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold25 mg
Light50–100 mg
Common100–200 mg
Strong200–300 mg
Heavy / risk zone≥ 300 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (oral)

Onset20–60 minutes
Come-up20–60 minutes
Peak210–300 minutes
Offset60–180 minutes
Afterglow120–360 minutes
Total300–600 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • Wakefulness
  • Reduced fatigue
  • Improved focus

Possible side effects

  • Headache
  • Insomnia
  • Anxiety
  • Nausea
  • Appetite loss
  • Rare but serious skin reactions - stop and seek advice if a rash appears

Known toxicity

  • The median lethal dose at which 50% of participants die (LD50) from modafinil for human beings has never been reached

Harm reduction

  • Test your substance. Cocaine, amphetamine and MDMA powders are routinely cut with fentanyl or nitazenes, and stimulant pills are frequently counterfeits.
  • Do not mix stimulants with each other, with alcohol, or with MAOIs, SSRIs or tramadol - the cardiovascular and serotonin risks compound.
  • Watch body temperature. Overheating and dehydration cause more stimulant emergencies than heart attacks do. Take breaks, cool down with water and air, and sip (do not gulp) fluids.
  • Eat and sleep. Sleep deprivation plus stimulants is the standard route into stimulant psychosis.
  • Do not re-dose compulsively. Set a maximum before you start, and give it to someone else to hold you to.
  • Chest pain, severe headache, one-sided weakness, slurred speech or fainting are medical emergencies. Call for help immediately.
  • Nasal use damages the septum and sinuses; chronic use causes permanent damage that does not heal.

Identify what you have

Marquis (reacts)yellow/orange > brown (116)
Mecke (reacts)orange > brown (156)
Mandelin (reacts)brownish red (15)
Liebermann (reacts)darkening orange (89)
Froehde (reacts)deep orange / red (10)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

25x-NBOMeDangerous

See interaction notes for details.

25x-NBOHDangerous

See interaction notes for details.

TramadolDangerous

See interaction notes for details.

MAOIsDangerous

See interaction notes for details.

Hormonal Birth ControlDangerous

See interaction notes for details.

CYP2C19-substratesDangerous

See interaction notes for details.

DXMUnsafe

See interaction notes for details.

MDMAUnsafe

See interaction notes for details.

StimulantsUnsafe

See interaction notes for details.

AlcoholCaution

See interaction notes for details.

MXECaution

See interaction notes for details.

DissociativesCaution

See interaction notes for details.

Tolerance, dependence and detection

Tolerancehalf tolerance after 3 - 7 days; back to baseline after 1 - 2 weeks
Addiction potentialnot addictive with a low potential for abuse
After-effects1-16

Sources

• PsychonautWiki — Modafinil (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/Modafinil

• TripSit wiki — Modafinil (PolyForm Noncommercial)
https://wiki.tripsit.me

• Erowid experience reports (external)
https://www.erowid.org/experiences/subs/exp_Modafinil.shtml

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.