Mephedrone

Stimulant

A synthetic cathinone with MDMA-like euphoria and stimulant drive but a much shorter duration and a strong compulsion to re-dose. Cardiovascular strain and nasal damage are common with repeated use.

4-MMCDroneM-CATMeow Meow4-mmcmeowm-cat4-methylmethcathinone4mmc

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0).

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold5 mg

Light15–45 mg

Common45–80 mg

Strong80–125 mg

Heavy / risk zone≥ 125 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (insufflated)

Onset5–8 minutes

Come-up15–30 minutes

Peak45–60 minutes

Offset30–90 minutes

Afterglow120–240 minutes

Total90–180 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

Euphoria
Empathy and talkativeness
Stimulation and energy
Increased sociability
Increased music appreciation
Increased libido

Possible side effects

Very strong compulsion to re-dose
Raised heart rate and blood pressure
Jaw clenching and bruxism
Profuse sweating
Anxiety and paranoia
Insomnia
Nasal pain and damage
Cold, blue extremities from vasoconstriction
Harsh crash

Known toxicity

exact toxic dosage is unknown

Harm reduction

Test your substance. Cocaine, amphetamine and MDMA powders are routinely cut with fentanyl or nitazenes, and stimulant pills are frequently counterfeits.
Do not mix stimulants with each other, with alcohol, or with MAOIs, SSRIs or tramadol - the cardiovascular and serotonin risks compound.
Watch body temperature. Overheating and dehydration cause more stimulant emergencies than heart attacks do. Take breaks, cool down with water and air, and sip (do not gulp) fluids.
Eat and sleep. Sleep deprivation plus stimulants is the standard route into stimulant psychosis.
Do not re-dose compulsively. Set a maximum before you start, and give it to someone else to hold you to.
Chest pain, severe headache, one-sided weakness, slurred speech or fainting are medical emergencies. Call for help immediately.
Nasal use damages the septum and sinuses; chronic use causes permanent damage that does not heal.

Identify what you have

Marquisno change or yellowish (254)

Meckeno color change (221)

Mandelin (reacts)short reddish (234)

Liebermann (reacts)yellow / orange (91)

Froehdeno color change (241)

Gallicno color change (212)

Ehrlichno color change (168)

Robadopeno pink color change (121)

Simon's (reacts)slow blue (61)

Hofmannno color change (137)

Zimmermann (reacts)purple ring / brown (17)

Morris (reacts)purple (14)

Scottblue spots (65)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.