DOSINA

Memantine

Dissociative

An NMDA-antagonist that if used recreationally can cause to a very prolonged "hole" lasting up to 16+ hours.

MemaxaEbixaNamendaNamenda XRNamzaric (with donepezilboth extended-release)

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.
⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold10 mg
Light30–70 mg
Common70–110 mg
Strong110–170 mg
Heavy / risk zone≥ 170 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (oral)

Onset30–180 minutes
Come-up120–180 minutes
Peak180–720 minutes
Offset300–1440 minutes
Afterglow480–1440 minutes
Total1080–2160 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • Long-lasting dissociation
  • Altered perception

Possible side effects

  • Dissociation lasting a day or more
  • Confusion
  • Dizziness
  • Nausea
  • Agitation
  • Other people can tell you are impaired

Known toxicity

  • exact toxic dosage is unknown

Harm reduction

  • Dissociation removes your sense of where your body is. Sit or lie down in a safe, warm place, away from stairs, balconies, bathtubs, roads and open water.
  • Never mix dissociatives with alcohol, GHB/GBL, benzodiazepines or opioids - that combination causes respiratory depression and deaths.
  • Do not use alone, and do not use in a bathtub or swimming pool at any dose.
  • Start with a fraction of the dose you think you need. Control and coordination go before you notice they have gone.
  • Frequent use of ketamine and similar drugs causes real bladder and urinary tract damage; early warning signs are pain, frequency and blood in urine.
  • Tolerance builds quickly and does not fully reset, which is how people end up at doses that were never safe to begin with.
  • Have someone check on you every 15-20 minutes during the peak, especially if you are lying down.

Identify what you have

Marquisno color change (254)
Mecke (reacts)grey (72)
Mandelin (reacts)short reddish (234)
Liebermannno color change (73)
Froehdeno color change (241)
Gallicno color change (212)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

StimulantsDangerous

See interaction notes for details.

DepressantsDangerous

See interaction notes for details.

Tolerance, dependence and detection

Addiction potentialunknown
After-effects1-72

Sources

• PsychonautWiki — Memantine (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/Memantine

• TripSit wiki — Memantine (PolyForm Noncommercial)
https://wiki.tripsit.me

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.