DOSINA

LSD

Psychedelic · popular

A classical psychedelic active in micrograms. Visual and perceptual distortion, intensely altered thinking, and effects that last most of a day. Dose is not weight-scaled, blotter strength varies, and the same dose can produce euphoria or fear depending on set and setting.

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Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0).

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.
⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold15 µg
Light15–75 µg
Common75–150 µg
Strong150–300 µg
Heavy / risk zone≥ 300 µg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (sublingual)

Onset15–30 minutes
Come-up45–90 minutes
Peak180–300 minutes
Offset180–300 minutes
Afterglow720–2880 minutes
Total480–720 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • Visual distortion, patterning and drifting
  • Enhanced colours and textures
  • Altered sense of time
  • Insight and introspection
  • Euphoria and mood lift
  • Increased music appreciation
  • Sense of connectedness
  • Enhanced sensory perception
  • Ego softening

Possible side effects

  • Anxiety and confusion
  • Paranoia at higher doses
  • Nausea
  • Dilated pupils
  • Raised heart rate and blood pressure
  • Insomnia for many hours
  • Difficulty communicating
  • Persisting visual changes with frequent use
  • Panic reactions in people vulnerable to psychosis

Known toxicity

  • extremely low toxicity relative to dose

Harm reduction

  • Assume blotter is around 100 µg, but treat unknown blotter as stronger rather than weaker, and start with half.
  • Test with Ehrlich reagent to confirm an indole; NBOMe compounds sold as LSD feel similar to beginners and are much more dangerous.
  • Set and setting, plus a trusted sober-ish person, matter more than the microgram count.
  • Effects last 8-12 hours. Do not plan anything demanding for the next day.
  • Cannabis on the peak is the single most common cause of an otherwise good trip turning difficult.
  • Do not mix with lithium - there are documented seizure and psychosis cases.
  • Set and setting shape a psychedelic experience more than the dose does. Plan the room, the music, the company and the exit before you take anything.
  • Have a sober person present, or at minimum someone who knows what you have taken and can be called.
  • Do not redose to 'make it stronger'. Tolerance to psychedelics develops within an hour, so a redose mostly extends the experience and increases the risk of a difficult one.
  • Avoid combinations with lithium (seizure risk) and tramadol, and be extremely careful with cannabis, which sharply intensifies the experience.

Identify what you have

Marquis (TripSit reference)Olive black
Marquisno instant reaction (254)
Meckeno instant reaction (221)
Mandelinno instant reaction (139)
Liebermannno instant reaction (73)
Froehdeno instant reaction (241)
Ehrlich (reacts)pink > purple (22)
Robadopeno pink color change (121)
Simon'sno blue color change (163)
Hofmann (reacts)blue (6)
Morris (reacts)pale green (77)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

LithiumDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

TramadolUnsafe

Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.

DeliriantsUnsafe

See interaction notes for details.

Tricyclic antidepressantsUnsafe

See interaction notes for details.

RitonavirUnsafe

See interaction notes for details.

CannabisCaution

Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

StimulantsCaution

Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences

cocaineCaution

Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences

2c-t-xLow risk

See interaction notes for details.

2c-xLow risk

See interaction notes for details.

5-meo-xxtLow risk

See interaction notes for details.

alcoholLow risk

See interaction notes for details.

Tolerance, dependence and detection

Toleranceback to baseline after 5 days
Addiction potentialnon-addictive with a low abuse potential
After-effects12-24

Sources

• PsychonautWiki — LSD (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/LSD

• TripSit wiki — LSD (PolyForm Noncommercial)
https://wiki.tripsit.me

• Erowid experience reports (external)
https://www.erowid.org/experiences/subs/exp_LSD.shtml

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.