DOSINA

Lithium

Medication

A prescription mood stabiliser. Included because it is one of the most dangerous things to combine with psychedelics, MDMA or stimulants, with documented seizure and serotonin syndrome cases.

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Not covered by PsychonautWiki — data comes from TripSit. Prescription or supplement entry — included for interaction checking, not as recreational dose guidance. Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.
⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

No structured dose data for this substance in our sources. Treat anything you read elsewhere with caution - unknown potency is the single biggest risk with novel substances.

Expected effects

  • Mood stabilisation (prescription medicine)

Possible side effects

  • Narrow therapeutic window - toxicity causes tremor, vomiting, confusion and seizures
  • Thyroid and kidney effects with long-term use
  • Seizure and psychosis risk when combined with psychedelics
  • Serotonin syndrome risk with MDMA

Harm reduction

  • Dosina shows prescription medicines so their interactions are visible - not so you can use them recreationally.
  • Never stop a prescribed medicine abruptly to take something else. Antidepressant discontinuation syndrome is real and can be severe; talk to your prescriber first.
  • SSRIs, SNRIs, MAOIs, lithium and tricyclics all interact with recreational drugs in ways that range from 'wastes your money' to 'kills you'.
  • Serotonin syndrome is the emergency to watch for: agitation, confusion, tremor, sweating, muscle rigidity, fever and a fast heartbeat after combining serotonergic drugs. It can become fatal within hours.
  • Keep any prescription medicine in its original packaging and never share it.

Mixing

2c-t-xDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

2c-xDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

dmtDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

doxDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

lsdDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

mdmaDangerous

High risk of serotonin syndrome

mescalineDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

mushroomsDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

nbomesDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

tramadolDangerous

Tramadol and Lithium both increase the risk of seizures and serotonin syndrome.

cocaineLow risk

Lithium may inhibit some of the recreational effects of cocaine.

nitrousLow risk

We are unable to find a report of concerns for CNS depression caused by Lithium.

Sources

• TripSit wiki — Lithium (PolyForm Noncommercial)
https://wiki.tripsit.me

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.