DOSINA

Ibuprofen

Supplement

A common anti-inflammatory painkiller. Not psychoactive. Included because it is often taken alongside other substances, where its stomach, kidney and bleeding risks matter.

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Not covered by PsychonautWiki — data comes from TripSit. Prescription or supplement entry — included for interaction checking, not as recreational dose guidance. Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

Dose

Published population range

Common400–800 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Expected effects

  • Pain relief and reduced inflammation (no psychoactive effect)

Possible side effects

  • Stomach irritation, ulcers and bleeding
  • Kidney strain, especially when dehydrated
  • Raised blood pressure
  • Interactions with alcohol, SSRIs and blood thinners
  • Not a sobering agent for anything, including hangovers

Harm reduction

  • Supplements are not risk-free. St John's Wort, 5-HTP, MAO-B and MAO-A inhibitors interact seriously with recreational drugs.
  • Never take 5-HTP at the same time as MDMA or other serotonin releasers - the combination is implicated in serotonin syndrome. At most it is used in the days after, and even that is debated.
  • Melatonin and L-theanine are sedating; that is fine for sleep but adds to depressant load if you have been drinking.
  • Dose information here reflects general-use amounts from the sources, not an endorsement of using them in combination with other drugs.

Sources

• TripSit wiki — Ibuprofen (PolyForm Noncommercial)
https://wiki.tripsit.me

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.