DOSINA

Diphenhydramine

Deliriant

A combination of diphenhydramine and a mild stimulant to counteract the drowsiness accompanied by typical medical use of diphenhydramine. Roughly half the potency of DPH. Small doses can relieve motion sickness, reduce body load from opioids or DXM. Becomes a deliriant in high doses, keeping the user awake and often causing dysphoric, realistic hallucinations.

DPHBenadrylNytolSominexUnisom SleepMeltsZzzQuildimenhydrinategravol

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

Dose

Published population range

Threshold25 mg
Light100–200 mg
Common200–400 mg
Strong400–700 mg
Heavy / risk zone≥ 700 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (oral)

Onset30–90 minutes
Come-up45–90 minutes
Peak60–240 minutes
Offset120–360 minutes
Afterglow-–1440 minutes
Total180–600 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • Sedation
  • Drowsy, heavy body feeling

Possible side effects

  • Delirium and frightening hallucinations
  • Tachycardia and hypertension
  • Dry mouth
  • Confusion
  • Restlessness and agitation
  • Seizures at high doses

Known toxicity

  • fatal at amounts close to or exceeding 2 grams

Harm reduction

  • Deliriants are the least recreational and most dangerous class in this app. Effects are usually frightening, and users cannot reliably tell delusion from reality.
  • Anticholinergic overdose - from DPH, dimenhydrinate or datura - causes seizures, dangerous overheating, heart rhythm problems and death. There is no safe ceiling once you are past the therapeutic dose.
  • Datura and scopolamine have killed people at doses nobody could predict. Plant potency varies enormously between leaves and between plants.
  • Never use these alone, and never in a place where you could wander into traffic, water or a height.
  • If someone is confused, hot, dry-skinned and has a racing heart after taking any of these, that is a medical emergency - call for help and say what was taken.

Identify what you have

Froehde (reacts)orange (16)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Tolerance, dependence and detection

Toleranceback to baseline after 1 - 2 weeks
Addiction potentialproduces dependence with chronic use

Sources

• PsychonautWiki — Diphenhydramine (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/Diphenhydramine

• TripSit wiki — Diphenhydramine (PolyForm Noncommercial)
https://wiki.tripsit.me

• Erowid experience reports (external)
https://www.erowid.org/experiences/subs/exp_Dimenhydrinate.shtml

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.