DMT

Psychedelic · popular

An intense, short-acting psychedelic - 5-20 minutes, usually smoked or vaporised. Overwhelming but brief, with profound perceptual and ego-altering effects.

N,N-DMTDmitryThe GloryThe Spirit Moleculen,n-dmtdimethyltryptamine

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0).

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold4 mg

Light4–10 mg

Common10–15 mg

Strong15–20 mg

Heavy / risk zone≥ 20 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (intravenous)

Onset0–0.2 minutes

Come-up1.2–1.7 minutes

Peak2–5 minutes

Offset10–20 minutes

Total15–30 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

Overwhelming visual and perceptual change
Ego dissolution
Profound insight or a sense of 'the other'
Time distortion
Euphoria
Auditory distortion

Possible side effects

Extremely overwhelming intensity and fear
Raised heart rate and blood pressure
Confusion afterwards
Nausea
Panic
Difficulty integrating the experience
Unsafe with hypertensive conditions

Known toxicity

extremely low toxicity

Harm reduction

Smoked or vaporised DMT hits in under a minute and is over in 5-20 minutes. Be sitting or lying down.
Have a sitter. Your body may move and you will not be tracking reality.
Do not combine with lithium, tramadol, SSRIs or MAOIs - the MAOI combination (ayahuasca-style) must follow its own strict dietary and medication rules.
One or two hits is a full experience. Chasing more mostly produces confusion.
Set and setting shape a psychedelic experience more than the dose does. Plan the room, the music, the company and the exit before you take anything.
Have a sober person present, or at minimum someone who knows what you have taken and can be called.
Do not redose to 'make it stronger'. Tolerance to psychedelics develops within an hour, so a redose mostly extends the experience and increases the risk of a difficult one.
Avoid combinations with lithium (seizure risk) and tramadol, and be extremely careful with cannabis, which sharply intensifies the experience.
People with a personal or family history of psychosis, schizophrenia or bipolar disorder should not use psychedelics - this is the clearest contraindication in the literature.
Never drive, cycle or operate machinery, and do not take psychedelics in public places or around crowds you cannot leave.

Identify what you have

Marquis (TripSit reference)Orange

Marquis (reacts)yellow > orange > brown (116)

Mecke (reacts)brown / green (63)

Mandelin (reacts)(faint) green > brown (234)

Liebermann (reacts)brown > black (121)

Froehdeno color change (241)

Ehrlich (reacts)pink > magenta / red (4)

Robadopeno pink color change (121)

Simon'sBlack precipitates with Simon A, no change with B (163)

Hofmann (reacts)yellow (31)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

LithiumDangerous

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

TramadolUnsafe

Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.

CannabisCaution

Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

StimulantsCaution

Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences

cocaineCaution

Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences

2c-t-xLow risk