DOSINA

Amphetamine

Stimulant · popular

A classic stimulant: alertness, energy, confidence and appetite suppression for 4-8 hours, with a hard crash. Adulteration with methamphetamine, caffeine or fentanyl is common.

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Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0).

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.
⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold4 mg
Light6–15 mg
Common15–30 mg
Strong30–50 mg
Heavy / risk zone≥ 50 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (insufflated)

Onset1–5 minutes
Come-up30–90 minutes
Peak60–120 minutes
Offset90–180 minutes
Afterglow120–240 minutes
Total180–360 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • Alertness and wakefulness
  • Energy and motivation
  • Euphoria
  • Improved focus
  • Confidence
  • Reduced appetite
  • Reduced need for sleep
  • Increased libido

Possible side effects

  • Compulsion to re-dose
  • Raised heart rate and blood pressure
  • Jaw clenching and bruxism
  • Insomnia
  • Anxiety and paranoia
  • Vasoconstriction
  • Crash with fatigue and low mood
  • Weight loss
  • Stimulant psychosis with sleep deprivation

Known toxicity

  • exact toxic dosage is unknown

Harm reduction

  • Test for methamphetamine and fentanyl contamination: stimulant powders are frequently not what they are sold as.
  • Eat before and during. Sleep afterwards. Skipping both is what turns a high into three days of paranoia.
  • Do not combine with MDMA, cocaine or other stimulants - the cardiovascular load compounds.
  • Set a maximum dose and a stop time before you start.
  • Nasal and oral use are less risky than smoking or injecting, but the dependence risk is real in all routes.
  • Test your substance. Cocaine, amphetamine and MDMA powders are routinely cut with fentanyl or nitazenes, and stimulant pills are frequently counterfeits.
  • Do not mix stimulants with each other, with alcohol, or with MAOIs, SSRIs or tramadol - the cardiovascular and serotonin risks compound.
  • Watch body temperature. Overheating and dehydration cause more stimulant emergencies than heart attacks do. Take breaks, cool down with water and air, and sip (do not gulp) fluids.
  • Eat and sleep. Sleep deprivation plus stimulants is the standard route into stimulant psychosis.
  • Do not re-dose compulsively. Set a maximum before you start, and give it to someone else to hold you to.

Identify what you have

Marquis (TripSit reference)Strong reddish orange - Dark reddish brown
Marquis (reacts)just orange spots (89)
Meckeyellow > black (221)
Mandelin (reacts)Neon green / blue (12)
Ehrlichno color change (168)
Robadope (reacts)pink (11)
Simon'sDark brown (163)
Hofmannno color change (137)
Zimmermannno color change (54)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

TramadolDangerous

See interaction notes for details.

aMTDangerous

See interaction notes for details.

MAOIsDangerous

See interaction notes for details.

DXMUnsafe

See interaction notes for details.

PCPUnsafe

See interaction notes for details.

25x-NBOMeUnsafe

See interaction notes for details.

2C-T-xUnsafe

See interaction notes for details.

5-MeO-xxTUnsafe

See interaction notes for details.

DOxUnsafe

See interaction notes for details.

AlcoholCaution

See interaction notes for details.

GHBCaution

See interaction notes for details.

OpioidsCaution

See interaction notes for details.

Tolerance, dependence and detection

Tolerancehalf tolerance after 3 - 7 days; back to baseline after 1 - 2 weeks
Addiction potentialhas high abuse potential and can cause psychological dependence with chronic use
Detection windowBlood: 12 hours. Saliva: ~3 days. Urine: 1-4 days. Hair: Up to 90 days.
After-effects1-12

Sources

• PsychonautWiki — Amphetamine (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/Amphetamine

• TripSit wiki — Amphetamine (PolyForm Noncommercial)
https://wiki.tripsit.me

• Erowid experience reports (external)
https://www.erowid.org/experiences/subs/exp_Amphetamines.shtml

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.