DOSINA

A-PVP

Stimulant

A potent, short-lasting pyrovalerone-type stimulant which became popular despite often being said to not be particularly euphoric, perhaps due to its propensity to cause compulsive redosing. Effects should be similar to MDPV.

α-PVPalpha-PVPFlakkaFlakO-2387β-ketone-prolintaneProlintanoneGravelalpha-pvpapvpalpha-Pyrrolidinopentiophenoneflocka

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.
⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold0.5 mg
Light1–5 mg
Common5–15 mg
Strong15–25 mg
Heavy / risk zone≥ 25 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (insufflated)

Onset10–30 minutes
Peak20–45 minutes
Offset30–90 minutes
Afterglow120–240 minutes
Total120–300 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • Intense euphoria
  • Powerful stimulation
  • Increased libido

Possible side effects

  • Extreme compulsion to re-dose
  • Psychosis and paranoia with prolonged use
  • Severe vasoconstriction
  • Cardiac events
  • Rhabdomyolysis
  • Violent or erratic behaviour reported

Known toxicity

  • exact toxic dosage is unknown

Harm reduction

  • Test your substance. Cocaine, amphetamine and MDMA powders are routinely cut with fentanyl or nitazenes, and stimulant pills are frequently counterfeits.
  • Do not mix stimulants with each other, with alcohol, or with MAOIs, SSRIs or tramadol - the cardiovascular and serotonin risks compound.
  • Watch body temperature. Overheating and dehydration cause more stimulant emergencies than heart attacks do. Take breaks, cool down with water and air, and sip (do not gulp) fluids.
  • Eat and sleep. Sleep deprivation plus stimulants is the standard route into stimulant psychosis.
  • Do not re-dose compulsively. Set a maximum before you start, and give it to someone else to hold you to.
  • Chest pain, severe headache, one-sided weakness, slurred speech or fainting are medical emergencies. Call for help immediately.
  • Nasal use damages the septum and sinuses; chronic use causes permanent damage that does not heal.

Identify what you have

Marquisfizzes clear (254)
Mecke (reacts)light yellow (67)
Mandelin (reacts)short reddish (234)
Liebermann (reacts)light yellow (91)
Froehde (reacts)faint yellow (78)
Gallicno color change (212)
Ehrlichno color change (168)
Simon'sno blue color change (163)
Hofmann (reacts)yellowish (31)
Zimmermann (reacts)yellow (20)
Morris (reacts)pale green (77)
Scott (reacts)blue (21)
Folin (reacts)orange (10)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

25x-NBOMeDangerous

See interaction notes for details.

25x-NBOHDangerous

See interaction notes for details.

TramadolDangerous

See interaction notes for details.

SNRIsDangerous

See interaction notes for details.

MAOIsDangerous

See interaction notes for details.

Serotonin releasersDangerous

See interaction notes for details.

SSRIsDangerous

See interaction notes for details.

5-HTPDangerous

See interaction notes for details.

DXMUnsafe

See interaction notes for details.

MDMAUnsafe

See interaction notes for details.

StimulantsUnsafe

See interaction notes for details.

AlcoholCaution

See interaction notes for details.

Tolerance, dependence and detection

Tolerancehalf tolerance after 3 - 7 days; back to baseline after 1 - 2 weeks
Addiction potentialhighly addictive with a high potential for abuse
After-effects1-48

Sources

• PsychonautWiki — A-PVP (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/A-PVP

• TripSit wiki — A-PVP (PolyForm Noncommercial)
https://wiki.tripsit.me

• Erowid experience reports (external)
https://www.erowid.org/experiences/subs/exp_aPVP.shtml

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.