DOSINA

4-AcO-DMT

Psychedelic

A prodrug for Psilocin with extremely similar effects as Mushrooms.

4-Acetoxy-DMTPsilacetinO-AcetylpsilocinSynthetic mushrooms4acodmtpsilacetin4-aco4-acetoxy-dmt

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.
⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold5 mg
Light10–15 mg
Common15–25 mg
Strong25–50 mg
Heavy / risk zone≥ 50 mg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (insufflated)

Onset5–25 minutes
Come-up30–60 minutes
Peak90–150 minutes
Offset60–90 minutes
Afterglow120 minutes
Total180–300 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • Psilocybin-like visual and emotional experience
  • Euphoria
  • Insight
  • Altered time perception

Possible side effects

  • Nausea on the come-up
  • Anxiety
  • Body load and muscle tension
  • Confusion
  • Unknown long-term safety profile (a research chemical)
  • Variable potency between batches

Known toxicity

  • toxic dose is unknown

Harm reduction

  • Set and setting shape a psychedelic experience more than the dose does. Plan the room, the music, the company and the exit before you take anything.
  • Have a sober person present, or at minimum someone who knows what you have taken and can be called.
  • Do not redose to 'make it stronger'. Tolerance to psychedelics develops within an hour, so a redose mostly extends the experience and increases the risk of a difficult one.
  • Avoid combinations with lithium (seizure risk) and tramadol, and be extremely careful with cannabis, which sharply intensifies the experience.
  • People with a personal or family history of psychosis, schizophrenia or bipolar disorder should not use psychedelics - this is the clearest contraindication in the literature.
  • Never drive, cycle or operate machinery, and do not take psychedelics in public places or around crowds you cannot leave.
  • Physically: expect dilated pupils, raised heart rate and reduced appetite. These are normal. Chest pain, fainting or seizure activity is not - get help.
  • Frequency matters: repeated use within days has sharply diminishing returns and increases the risk of persistent visual disturbances.

Identify what you have

Marquis (reacts)yellow > green > brown (116)
Mecke (reacts)yellow > (dark) green (72)
Mandelin (reacts)yellow > black (87)
Liebermann (reacts)brown > black (121)
Froehde (reacts)green > black (36)
Gallic (reacts)light brown (50)
Ehrlich (reacts)Light purpleish (22)
Simon'sno blue color change (163)
Hofmann (reacts)yellow (31)
Morris (reacts)pale green (77)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

LithiumDangerous

See interaction notes for details.

TramadolUnsafe

See interaction notes for details.

CannabisCaution

See interaction notes for details.

StimulantsCaution

See interaction notes for details.

Tolerance, dependence and detection

Toleranceback to baseline after 7 days
Addiction potentialnon-addictive with low potential for abuse
After-effects1-12

Sources

• PsychonautWiki — 4-AcO-DMT (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/4-AcO-DMT

• TripSit wiki — 4-AcO-DMT (PolyForm Noncommercial)
https://wiki.tripsit.me

• Erowid experience reports (external)
https://www.erowid.org/experiences/subs/exp_4AcODMT.shtml

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.