25I-NBOMe

Psychedelic

A relatively new and popular research chemical with psychedelic properties. Users report an uncomfortable body load with very strong visuals, though with less of a mental aspect than most psychedelics. Commonly mis-sold as LSD, since it is much cheaper to produce. Is considered quite unsafe, and has caused several deaths at 'regular' doses.

25iCimbi-52-c-i-nbome25-i

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance's dose is not reliably weight-scaled - the ranges shown are population figures. Sensitivity varies far more between people than body mass explains.

⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold50 µg

Light200–500 µg

Common500–700 µg

Strong≥ 700 µg

No weight-based model for this substance — published ranges only.

Check an amount you already have

Timeline (insufflated)

Onset5–10 minutes

Come-up10–30 minutes

Peak60–120 minutes

Offset120–180 minutes

Afterglow1440–10080 minutes

Total240–360 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

Visual and perceptual effects, sold as LSD

Possible side effects

Severe vasoconstriction
Seizures
Hyperthermia
Cardiac arrest
Multiple confirmed deaths
Frequently mis-sold as LSD blotter

Known toxicity

potentially fatal at heavy dosages

Harm reduction

Set and setting shape a psychedelic experience more than the dose does. Plan the room, the music, the company and the exit before you take anything.
Have a sober person present, or at minimum someone who knows what you have taken and can be called.
Do not redose to 'make it stronger'. Tolerance to psychedelics develops within an hour, so a redose mostly extends the experience and increases the risk of a difficult one.
Avoid combinations with lithium (seizure risk) and tramadol, and be extremely careful with cannabis, which sharply intensifies the experience.
People with a personal or family history of psychosis, schizophrenia or bipolar disorder should not use psychedelics - this is the clearest contraindication in the literature.
Never drive, cycle or operate machinery, and do not take psychedelics in public places or around crowds you cannot leave.
Physically: expect dilated pupils, raised heart rate and reduced appetite. These are normal. Chest pain, fainting or seizure activity is not - get help.
Frequency matters: repeated use within days has sharply diminishing returns and increases the risk of persistent visual disturbances.

Identify what you have

Marquis (TripSit reference)Orange

Marquis (reacts)brown > dark brown (116)

Mecke (reacts)brown > black (72)

Mandelin (reacts)brown (234)

Liebermann (reacts)yellow > black (121)

Froehde (reacts)yellow (78)

Gallic (reacts)brown (50)

Ehrlichno color change (168)

Simon'sno blue color change (163)

Hofmannno color change (137)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.