DOSINA

1,4-Butanediol

Depressant

1,4-BD is a clear liquid with intoxicating effects. It is a pro-drug for GHB, and has similar though reportedly inferior effects. It also carries the potential for more health risks than GHB, such as liver toxicity.

1,4-BBDBDOOne Comma FourOne Four BeeButylene GlycolOne Four B-D-Obd1,4-bd14bd

Dose and effect data: PsychonautWiki (CC BY-SA 4.0) and TripSit (PolyForm Noncommercial 1.0.0). Less-used substance: fewer independent sources, so treat these numbers with extra caution.

Before you dose

⚠This substance has combinations that are life-threatening. Check the Interactions tab before mixing anything.

Dose

Published population range

Threshold0.5 ml
Light0.5–1 ml
Common1–2.5 ml
Strong2.5–4 ml
Heavy / risk zone≥ 4 ml

Basis: Scaled from the published 70 kg range.

Converted to GHB in the body; onset is slower and less predictable than GHB itself.

Showing published ranges.

Check an amount you already have

Timeline (oral)

Onset20–60 minutes
Peak60–120 minutes
Offset90–120 minutes
Afterglow120–240 minutes
Total180–300 minutes

Bars show relative time in each phase, scaled to the total duration. Each phase keeps its colour in the list above.

Expected effects

  • GHB-like euphoria and relaxation
  • Sociability

Possible side effects

  • Slower, less predictable onset than GHB - re-dosing too early is the main risk
  • Nausea
  • Unconsciousness
  • Respiratory depression when mixed with depressants
  • Severe dependence and withdrawal

Known toxicity

  • exact toxic dosage is unknown

Harm reduction

  • Depressants are the class where mixing kills most often: alcohol, benzodiazepines, GHB/GBL and opioids all suppress breathing when combined.
  • Never use alone. If you use alone, set up a check-in call with someone who will call emergency services if you do not answer.
  • Measure liquid doses with a syringe. Bottle caps, teaspoons and 'glugs' are how people take ten times the intended dose.
  • Sedation can be delayed. Do not re-dose before you can feel the previous dose fully.
  • Do not stop daily benzodiazepine or alcohol use abruptly - withdrawal can cause seizures and is potentially fatal. Taper with medical help.
  • Signs that someone needs emergency help: breathing slower than one breath every 4-5 seconds, blue lips, snoring that will not stop, unrousable, vomiting while unconscious.

Identify what you have

Marquisno color change (254)
Mandelin (reacts)brown (234)
Liebermann (reacts)purple-blue (3)
Froehdeno color change (241)
Ehrlichno color change (168)

Reagent tests show what a substance probably is, not how pure it is or what else is in the mix. Fentanyl and nitazene test strips are the only reliable check for those, and quantitative lab testing is better than both.

Mixing

DepressantsDangerous

See interaction notes for details.

DissociativesDangerous

See interaction notes for details.

StimulantsCaution

See interaction notes for details.

Tolerance, dependence and detection

Toleranceback to baseline after 7 - 14 days
Addiction potentialmoderately physically and psychologically addictive
After-effects2-4

Sources

• PsychonautWiki — 1,4-Butanediol (CC BY-SA 4.0)
https://psychonautwiki.org/wiki/1%2C4-Butanediol

• TripSit wiki — 1,4-Butanediol (PolyForm Noncommercial)
https://wiki.tripsit.me

• Erowid experience reports (external)
https://www.erowid.org/experiences/subs/exp_14Butanediol.shtml

Dosina is educational harm-reduction information, not medical advice. Doses are population ranges from published sources and cannot account for your tolerance, health conditions or what is actually in your substance. Possession and use may be illegal where you live.